Vesicles' Role in T Cell Activation Uncovered (2 of 3) (VIDEO)

American Association for the Advancement of Science (AAAS)

Caption

This is TIRF imaging of Vav1 and CRACR2A-a at the plasma membrane of a spreading Jurkat cell. This material relates to a paper that appeared in the March 22, 2016 issue of Science Signaling, published by AAAS. The paper, by S. Srikanth at University of California, Los Angeles in Los Angeles, CA, and colleagues was titled, "A large Rab GTPase encoded by CRACR2A is a component of subsynaptic vesicles that transmit T cell activation signals."

Credit

S. Srikanth <i>et al., Science Signaling</i> (2016)

Usage Restrictions

Please cite the owner of the material when publishing. This material may be freely used by reporters as part of news coverage, with proper attribution. Non-reporters must contact <i>Science</i> for permission.

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.