Klotho and Water Maze Test (IMAGE) Cell Press Caption This illustration shows how klotho treatment in mice rapidly improved learning and memory of a hidden platform in a water maze. Credit Leon et al. Usage Restrictions Credit Required. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.