Getting Cells to Move (IMAGE)

Cincinnati Children's Hospital Medical Center

Getting Cells to Move

Caption

These images from scientists at Cincinnati Children's show hematopoietic stem cells (blood stem cells) from donor laboratory mice. The donor stem cell harvested from a mouse treated with the preclinical drug CASIN (bottom) is depolarized with several colored polarity markers -- giving it better mobilization potential than the untreated stem cell in the top image. The scientists report in the journal <em>Leukemia</em> that preclinical data show CASIN treatment has the potential to make life-saving bone marrow transplant procedures safer and more effective for patients.

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Cincinnati Children's

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