Wisent Gene Selection (IMAGE)
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Their comparison of the wisent and bovine genomes also revealed footprints of selection on more than 400 genes. Overall, the most significant functions associated to these genes are related to physiological functions underlying distinctive features between the bison and bovine lineages (i.e. nervous system, immune and inflammatory responses, reproduction and embryonic development, cellular morphology and organization and skeletal and muscular disorders). Among individual genes, KRT74 and DCS3 that are involved in wooly hair development and hypotrichosis, respectively and GPR50 that plays a role in thermogenesis might be directly related to wisent adaptation.
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(copyright: Rafa? Kowalczyk)
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