Henry VIII and his Wives (IMAGE) Southern Methodist University Caption Blood group incompatibility between Henry VIII and his six wives could have driven the Tudor king's reproductive woes, and a genetic condition related to his blood group could finally provide an explanation for his dramatic physical and mental changes at mid-life Credit tudorhistory.org Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.