GITs Proteins Exert a Critical Control Regulating the Strength of Synaptic Transmission (IMAGE)

Max Planck Florida Institute for Neuroscience

GITs Proteins Exert a Critical Control Regulating the Strength of Synaptic Transmission

Caption

Presynaptic deletion of the two G-protein-coupled receptor kinase-interacting proteins (GITs), GIT1 and GIT2, at the mouse calyx of Held, leads to a large increase in the action potential (AP)-evoked release, resulting in increase of synaptic strength.

Credit

Mónica S. Montesinos and Samuel M. Young Jr./Max Planck Florida Institute for Neuroscience.

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