Chromosome Pairing Is Crippled in Some Unstable Cancer Cells (IMAGE)

American Association for the Advancement of Science (AAAS)

Chromosome Pairing Is Crippled in Some Unstable Cancer Cells

Caption

A lung cancer cell shows lagging chromosomes in mitotic anaphase, a hallmark of chromosomal instability, which may drive tumor progression. Chromosomes (red) and kinetochore (green) were immunostained. This material relates to a paper that appeared in the Sept. 11, 2015 issue of Science, published by AAAS. The paper, by Y. Tanno at University of Tokyo in Tokyo, Japan, and colleagues was titled, "The inner centromere-shugoshin network prevents chromosomal instability."

Credit

Miyuki Kawamura

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