Genetically Modified Pigs Resist Infection with the Classical Swine Fever Virus (IMAGE)
Caption
Fig 6. TG pigs exhibit antiviral responses during CSFV infection. H. Histopathological changes in the NTG pigs were confirmed by HE staining. These histopathological changes included a decrease in splenic white pulp and hyperaemia; an expansion of splenic red pulp; acidophilic change and accumulation of lipid droplets in hepatocytes; infiltration of inflammatory cells in the portal area of the liver; alveolar effusion, bleeding and infiltration of a large number of inflammatory cells in the lungs; and unclear renal tubular epithelial cell boundaries; and cell cavitation in the kidneys.
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Xie Z, et al. (2018)
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