Chip (IMAGE)

University of California - Berkeley

Chip

Caption

To harness CRISPR's gene-targeting ability, the researchers took a deactivated Cas9 protein -- a variant of Cas9 that can find a specific location on DNA, but doesn't cut it -- and tethered it to transistors made of graphene. When the CRISPR complex finds the spot on the DNA that it is targeting, it binds to it and triggers a change in the electrical conductance of the graphene, which, in turn, changes the electrical characteristics of the transistor.

Credit

Keck Graduate Institute

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