Damage to SCA6 Purkinje Cells Is Suppressed (IMAGE)
Caption
High magnification images of L7+ Purkinje cells (green) derived from control (top), SCA6 heterozygous (middle) and SCA6 homozygous (bottom) iPSCs on culture day 75 are shown. Note the dendritic degradation when SCA6 cells are deprived of thyroid hormone T3, and the lack of degradation when thyroid releasing hormone (THR) or Riluzole are present. Scale bars, 200 μm.
Credit
RIKEN
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credit RIKEN
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