A Cancer Drug Candidate Protects Neurons Against Alzheimer's in Mice (1 of 1) (IMAGE)

American Association for the Advancement of Science (AAAS)

A Cancer Drug Candidate Protects Neurons Against Alzheimer's in Mice (1 of 1)

Caption

A pyramidal neuron in the hippocampus. Inhibiting LIMK1 prevented the loss of thin spines in hippocampal neurons in a mouse model of amyloid beta accumulation. This material relates to a paper that appeared in the June 26, 2019, issue of Science Translational Medicine, published by AAAS. The paper, by B.W. Henderson at Birmingham School of Medicine in Birmingham, AL; and colleagues was titled, "Pharmacologic inhibition of LIMK1 provides dendritic spine resilience against amyloid-β."

Credit

B.W. Henderson <i>et al., Science Signaling</i> (2019)

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