Monoamine Model of Postpartum Blues (IMAGE)

Max-Planck-Gesellschaft

Monoamine Model of Postpartum Blues

Caption

Monoamine model of postpartum blues. A: After delivery, estrogen levels drop 100- to 1000fold; the estrogen decline is greatest during the first 3 to 4 days postpartum, with a modest decline thereafter. B: Monoamine oxidase A levels are significantly greater in the early postpartum period, with a peak on day 5 postpartum. C: In the early postpartum period, up to 70 percent of mothers experience sadness, mood lability, anxiety, insomnia, poor appetite, and irritability, with mood being lowest on day 5 postpartum.

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Image: Max Planck Institute for Human Cognitive and Brain Sciences

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