Contraction Drives PAR Protein Clustering to Break Symmetry (IMAGE)

National University of Singapore

Contraction Drives PAR Protein Clustering to Break Symmetry

Caption

Figure: Contraction drives PAR protein clustering to break symmetry in a C. elegans embryo. The top image shows the contractile activity of cortical myosin, which causes clustering of PAR-3 protein (bottom image). Both myosin and PAR-3 segregate at the left side of the embryo, the anterior pole. This breaks the previous symmetrical distribution of these proteins and polarises the cell.

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Mechanobiology Institute, Singapore

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