3-D Fluorescence Microscopy Image of EphA2 (IMAGE)
Caption
This is a 3-D fluorescence microscopy image of a cell guidance receptor's (EphA2) signaling activity in a cryo-arrested cell. This receptor is overexpressed in melanomas and affects metastasis. From this image taken at subzero temperatures, one can see that it is transmitting its signals from small vesicles in the cell that get internalized from the plasma membrane. The color code indicates the signaling activity of the receptor.
Credit
MPI f. Molecular Physiology
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