Proposed Mechanism for the Development of Obesity (IMAGE)

Baylor College of Medicine

Proposed Mechanism for the Development of Obesity

Caption

The scientists have shown a new mechanism by which the brain can regulate the development of obesity triggered by consuming a high-fat diet. Consuming a high-fat diet results in changes in the brain that increase Rap1 activity, which in turn leads to a decreased sensitivity to leptin, and this sets the body on a path to obesity.

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Courtesy M. Fukuda/Cell Reports

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