Genome Sequencing from the Womb (1 of 3) (IMAGE)
Caption
Sequencing of fetal and total DNA in maternal plasma. Sequencing depth and GC content across the whole genome. Chromosome ideograms (outer ring) are oriented pter-qter in a clockwise direction (centromeres are shown in yellow). Other tracks (from outside to inside): GC content (green; range, 30 to 55 percent), total sequencing depth (red; range, 40 to 100 reads per SNP), and fetal-specific read sequencing depth (blue; range, 1 to 8 reads per SNP). For more information, please see Figure 2 in the manuscript. This image relates to an article that appeared in the Dec. 8, 2010, issue of Science Translational Medicine, published by AAAS. The study, by Y.M. Dennis Lo at the Chinese University of Hong Kong in Hong Kong, China, and colleagues was titled, "Maternal Plasma DNA Sequencing Reveals the Genome-Wide Genetic and Mutational Profile of the Fetus."
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[Image courtesy of <i>Science</i>/AAAS]
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