MEMOIR Cells (IMAGE) California Institute of Technology Caption MEMOIR enables the histories of cells to be recorded in their genomes and then read out using microscopy. Here, MEMOIR cells were variably activated, as seen by the bright cyan nuclear fluorescence in some cells. The cells recorded information in response to this signal with the help of a DNA-editing system called CRISPR. This recorded information can then be read out using a technique called seqFISH to visualize certain RNA transcripts in the cells (red dots). Credit Elowitz and Cai Labs/Caltech Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.