The Spliceosome in the Spotlight (IMAGE)
Caption
The researchers have simulated and analysed the movements of a specific and crucial set of protein/RNA complexes, understanding its role and establishing in particular that a protein called Spp42 (Prp8 in human) carries out a crucial role. Its action essentially induces the movement and hence regulate the function of all the other spliceosome components, namely an enormous machinery composed of more than 100 proteins and 5 filaments of RNA».
Credit
Alessandra Magistrato
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