New Pathway is a Common Thread in Age-Related Neurodegenerative Diseases (IMAGE)
Caption
Over time, protein aggregates (shown in green) accumulate in the axons of MOCA-deficient mice. They start out small, initially causing few or no symptoms, but as they built up in the axons, they begin to destroy the cytoskeleton, the internal framework of the cells, increasingly interfering with the transmission of signals from the nerve cells. Eventually the affected axons die, followed by the death of the nerve cell itself.
Credit
Image: Courtesy of Dr. Qi Chen, Salk Institute for Biological Studies.
Usage Restrictions
News media reproduction to illustrate this story permitted with proper attribution as provided above. For one time use only.
License
Licensed content