CFTR Functionality (IMAGE)
Caption
A new JGP study provided evidence about the functionality of CFTR, a protein that plays a critical role in cystic fibrosis. Here, an updated model illustrates the relationship between an opening/closing cycle of the gate and ATP consumption in CFTR’s nucleotide-binding domains.
Credit
Jih, K.-Y., et al. 2012. <i>J. Gen. Physiol.</i> 140:347–359.
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