PPIs (IMAGE) Washington University School of Medicine Caption Millions of US residents take proton pump inhibitors which are widely prescribed to treat heartburn, ulcers and other gastrointestinal problems. The drugs also are available over the counter under brand names that include Prevacid, Prilosec and Nexium. Now, a new study from Washington University School of Medicine in St. Louis shows that long-term use of the popular drugs carries an increased risk of death. Credit Robert Boston Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.