Princeton Chemistry: Photoredox- and Enzyme-Mediated Dynamic Kinetic Resolution (IMAGE)

Princeton University

Princeton Chemistry: Photoredox- and Enzyme-Mediated Dynamic Kinetic Resolution

Caption

The overall transformation combining racemization of the ketone substrates (left) with biocatalytic reduction to enantiomerically pure alcohol products (center), and the key enaminyl radical species this chemistry unlocks to enable the racemization of typically static β-ketostereocenters (right).

Credit

Jacob DeHovitz

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