Figure 1 (IMAGE) Kanazawa University Caption Changes in body core temperature (A) and hypothalamic interstitial PGE2 concentration (B) in mice injected with lipopolysaccharide (LPS). LPS was intraperitoneally injected to Slco2a1+/+ or Slco2a1-/- mice at time 0 hr. Body temperature was measured by monitoring colonic temperature. For PGE2 measurements, samples were collected by means of microdialysis, and subjected to LC-MS/MS analysis. (A) and (B) show mean values ± S.E.M of 10 and 6 mice in each group, respectively. Credit Kanazawa University Usage Restrictions The image may only be used with appropriate caption and credit. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.