Strong Immune Response Can't Keep CMV Down (1 of 2) (IMAGE)

American Association for the Advancement of Science (AAAS)

Strong Immune Response Can't Keep CMV Down (1 of 2)

Caption

Superinfection: infection with a strain of CMV triggers an immune response, including the activation and expansion of cytotoxic CD8+ T cells. The virus persists mainly in the latent form. A secondary infection by the same or similar CMV occurs if the secondary virus blocks MHC class I antigen presentation to the virus-specific CD8+ T cells. This image relates to an article that appeared in the April 2, 2010, issue of Science, published by AAAS. The Perspective paper, by Dr. Hartmut Hengel of Heinrich-Heine-University in Düsseldorf, Germany, and Dr. Ulrich H. Koszinowski of Ludwig-Maximilians-University in Munich, Germany, was titled, "A Vaccine Monkey Wrench?"

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N. Greenman/<i>Science</i>

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