Replicative Helicase Binds to DNA Strand (IMAGE)

Advanced Science Research Center, GC/CUNY

Replicative Helicase Binds to DNA Strand

Caption

Loader proteins (orange) attach to the DnaB replicative helicase (white), causing it to briefly spiral open. Opening of the helicase enables entry of one of the DNA molecule's two strands. Once activated, the helicase runs the length of the strand, separating them and initiating the replication process. Here, the helicase -- helicase loader complex is shown atop a set of cryogenic electron microscopy images used to visualize the structure.

Credit

Jillian Chase and David Jeruzalmi

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