usher_SANS (IMAGE) Johannes Gutenberg Universitaet Mainz Caption SANS is essential for the release of tri-snRNPs from the Cajal bodies and their transfer to the nuclear speckles. There the spliceosome is assembled and subsequently activated. Therefore, SANS plays a crucial role in correct pre-RNA splicing as a whole. Credit ill./©: Uwe Wolfrum Usage Restrictions This image may only be used in connection with the press release "Remarkable new insights into the pathology of Usher syndrome", issued by Johannes Gutenberg University Mainz on July 12, 2021. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.