Nanobiosensor Prototype Capable of Detecting Interactions between Molecules (IMAGE)

World Scientific

Nanobiosensor Prototype Capable of Detecting Interactions between Molecules

Caption

A nanobiosensor prototype capable of detecting interactions between molecules is being proposed and characterized. The analyzed system was composed by 4-hydroxyphenylpyruvate dioxygenase (HPPD) enzyme and its inhibitor, mesotrione herbicide. A method based on Atomic force microscope mesotrione-functionalized-cantilever was employed to detect the interaction of herbicide molecules with HPPD enzyme. This detection was related to a surface stress on the functionalized cantilever generated by enzyme-herbicide binding. Tests showed that the prototype was specific to detect mesotrione-HPPD interaction.

Credit

Fabio L. Leite

Usage Restrictions

Citation of article and journal is required.

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.