Brain Tumor Cells Decimated by Mitochondrial (IMAGE)
Caption
The new drug MP-MUS (yellow) attacks cancer cell mitochondria by infiltrating both inner and outer membranes (green) after being converted from an inactive, non-toxic form to an active, toxic form by the enzyme MAO-B (purple). Once inside, the drug damages mitochondrial DNA, which cannot be repaired.
Credit
Dr. David Baskin laboratory, Houston Methodist Hospital
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