Dose-dependent occupancy of D1-like receptors following administration of D1R selective blocker (IMAGE)

The National Institutes for Quantum Science and Technology

Dose-dependent occupancy of D1-like receptors following administration of D1R selective blocker

Caption

Positron emission tomography (PET) imaging was used to assess the pharmacological manipulation of dopamine receptors in monkeys. The degree of blockade of either D1R or D2R was associated with a reduction in the positive impact of reward amount and increasing delay discounting while performing a task.

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Image courtesy: Yukiko Hori from National Institutes for Quantum and Radiological Science and Technology

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