Figure 7 (IMAGE)

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Figure 7

Caption

IPA ATM-signaling pathway in (A) EFV treated MRC-5 and (B) A549 cells. The green and the red colours indicate down and up-regulation. The activated p53 irrespective of the expression levels of ATM activates its downstream targets such as p21, GADD45A, BRCA1 and NBS, inhibiting cell cycle progression and initiating DNA repair and growth arrest mechanisms.

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Correspondence to - Rahaba Marima - rahaba.marima@up.ac.za

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