Figure 9 (IMAGE) Impact Journals LLC Caption Effect of palmitoyl-lysophosphatidylcholine LPC[16:0] on tumor spheroid invasion and growth. 3D cell spheroids of hypopharynx squamous cell carcinoma origin were embedded in Matrigel matrix. Invasion and growth of spheroids are shown in the presence of increasing concentration of LPC[16:0] at 264 h. (A) Example images of spheroid cross-sections. (B) Size of spheroid cross-section areas are shown relative to values at 0 h (when embedding in Matrigel). Total spheroid size equals to the proliferative - necrotic core and the invasive zone. 95% CI is displayed, asterisks indicate statistical significance relative to control values. Credit Correspondence to - Zsolt Balogi - zsolt.balogi@aok.pte.hu and László Márk - laszlo.mark@aok.pte.hu Usage Restrictions CCBY License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.