Figure 5 (IMAGE)

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Figure 5

Caption

MASPIN can prevent the formation of UPA - UPA-receptor complex by a single step, and thus decrease the possibility of the abnormal degradation of the ECM, the development metastasis and angiogenesis. (UPA: urokinase type plasminogen activator, UPAR: UPA-receptor, HIF1A: hypoxia-inducible factor 1 alpha ECM: extracellular matrix, RAS: GTP-binding protein, RAC: subfamily of RHO-GTP-ases).

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Correspondence to - Gabor Halmos - halmos.gabor@pharm.unideb.hu

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