Figure 6 (IMAGE)
Caption
Clinical data analyses from TCGA reveal distinct patient subgroups with elevated PTGR1 that are likely to be predicted responders to LP-184. (A) Analysis of clinical data on 517 lung adenocarcinoma patients shows frequency of mutated genes across the observed PTGR1 relative gene expression range. The value adjacent to the highly mutated gene is a two-sided permutation test p-value of PTGR1 relative gene expression between driver mutated (red) and non-mutated (white) samples. (B) Analysis of clinical data on the same 517 lung adenocarcinoma patients as in (A) displays patient subsets by PTGR1 expression status, and mutational frequencies of selected driver genes within the PTGR1 elevated subset.
Credit
Correspondence to - Aditya Kulkarni - aditya@lanternpharma.com
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Copyright: © 2021 Kulkarni et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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