Figure 14 (IMAGE) Impact Journals LLC Caption A hypothetical model of how a specific remodeling of cellular metabolism by CR slows down yeast chronological aging. See the text for more details. Abbreviations: Cys, cysteine; Met, methionine; Ppa2p, inorganic pyrophosphatase 2; Sam, S-adenosylmethionine; Snf1, sucrose non-fermenting complex 1; Tor1, target of rapamycin complex 1. Credit Correspondence to - Vladimir I. Titorenko - vladimir.titorenko@concordia.ca Usage Restrictions https://www.oncotarget.com/article/27926/text/ License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.