Pancreatic Cancer Cells (IMAGE)

Cold Spring Harbor Laboratory

Pancreatic Cancer Cells

Caption

Most pancreatic cancer cells have mutations in the KRAS gene that allow unregulated growth. In this image, the mutant, cancer-causing version of the KRAS protein is stained red in pancreatic cancer cells. KRAS outlines the plasma membrane -- the outer layer of the cell. Cell nuclei are stained blue. Cold Spring Harbor Laboratory researchers discovered a new mechanism that might explain how pancreatic cancer cells develop resistance to drug treatments that target the KRAS protein.

Credit

Derek Cheng/Tuveson lab/CSHL, 2021

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