Mice lacking the ketogenesis function develop fatty livers early in life (IMAGE)

Kumamoto University

Mice lacking the ketogenesis function develop fatty livers early in life

Caption

Ketogenesis-deficient mice lacking the gene for HMG-CoA Synthase 2 (HMGCS2) (bottom row) develop severely fatty liver starting in the neonatal period.

Credit

Dr. Yuichiro Arima

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(Fig. 3d) Reprinted by permission from Springer Nature Customer Service Centre GmbH: Springer Nature, Nature Metabolism, <a href="https://www.nature.com/articles/s42255-021-00342-6" target="_blank">Murine neonatal ketogenesis preserves mitochondrial energetics by preventing protein hyperacetylation, Yuichiro Arima et. al., 18 February 2021</a> (2021) DOI: 10.1038/s42255-021-00342-6

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