Figure 1 (IMAGE) Impact Journals LLC Caption Flowchart of trial screening and inclusion. Of 1877 trials identified on https://clinicaltrials.gov/ (February 20, 2020), 841 were excluded, for a final total of 1036 phase III randomized clinical trials assessing therapeutic interventions in patients with cancer. Of those, 790 trials had peer-reviewed manuscripts of primary study endpoint, and were included in primary analysis for this manuscript. Credit Correspondence to - Cullen M. Taniguchi - ctaniguchi@mdanderson.org and Ethan B. Ludmir - ebludmir@mdanderson.org Usage Restrictions Credit must be given to the creator. License CC BY Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.