Selectivity hotspot map (IMAGE)

CCDC - Cambridge Crystallographic Data Centre

Selectivity hotspot map

Caption

Hotspot maps use empirical data to assess protein binding sites to understand the druggability of the pocket, prioritize drug design, and spot differences in similar proteins that might drive compound selectivity.

Credit

Mihaela D Smilova, co-author and postgraduate researcher at the Centre for Medicines Discovery at Oxford University

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License

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