Selectivity hotspot map (IMAGE) CCDC - Cambridge Crystallographic Data Centre Caption Hotspot maps use empirical data to assess protein binding sites to understand the druggability of the pocket, prioritize drug design, and spot differences in similar proteins that might drive compound selectivity. Credit Mihaela D Smilova, co-author and postgraduate researcher at the Centre for Medicines Discovery at Oxford University Usage Restrictions None License Original content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.