TPC1 Channel Pore (IMAGE) University of Würzburg Caption 3-Dimensional sketch of the TPC1 channel protein looking at the vacuolar pore entrance from above. Positional changes of amino acid residues such as E605 during the transition from a closed channel state to a partially open pore state. Credit Thomas Mueller / University of Wuerzburg Usage Restrictions none License Original content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.