Malfunctioning Neurons (IMAGE) Harvard Medical School Caption Normally, U2-snRNP (red) is found in the nucleus of motor neurons (left), but it accumulates outside the nucleus in the neurons of patients with ALS and frontotemporal dementia who have a certain genetic mutation. Credit Reed Lab/Harvard Medical School Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.