Sleep and the Unfolded Protein Response (IMAGE) University of Pennsylvania School of Medicine Caption The effect of sleep and social isolation on protein folding. Credit Michael Paolini & Sarah Ly. Adpated from Colwell (2007) Nature Neuroscience Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.