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In Drosophila, octopamine signaling increases larval locomotor speed and synaptic bouton numbers at neuromuscular junctions under food deprivation conditions. We found that a glypican (Dally-like), the expression of which is controlled by octopamine signaling, regulates this process by modulating the activity of GluRIIA-mediated non-canonical BMP pathway.
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Tokyo Metropolitan Institute of Medical Science
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