Influenza A NS1 Binding Pocket (IMAGE)

Rutgers University

Influenza A NS1 Binding Pocket

Caption

Image generated using X-ray crystallography shows binding pocket for the human CPSF30 protein on the influenza A virus NS1 protein (brown), with a fragment of the CPSF30 protein (blue) bound in the pocket. Work published this week in the Proceedings of the National Academy of Sciences reveals this interaction is a target for antiviral drug discovery.

Credit

K. Das, L. Ma, E. Arnold, R, Krug, G. Montelione and others, Rutgers University and The University of Texas at Austin

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