Senescence and Parkinson's (IMAGE)

Buck Institute for Research on Aging

Senescence and Parkinson's

Caption

In post-mortem samples from individuals with Parkinson's, brain cells called astrocytes show evidence of cellular senescence. Senescent cells loose a specific protein from their nuclei; this protein is indicated with the green signal in the image above. This protein is lost from astrocytes (red cells), but not from neighboring cells. Note that astrocytes do not appear to become senescent in control individuals -- on the left.

Credit

Georgia Woods, PhD Buck Institute for Research on Aging

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