Fusing Cells (IMAGE)

Johns Hopkins Medicine

Fusing Cells

Caption

When the fusogenic protein Eff-1 was expressed, a few normally nonfusing cells merged (left). But when Eff-1 was expressed with a protein that could organize cytoskeleton remodeling, fusion was rampant, leading to the formation of giant cells with many nuclei (right).

Credit

From K. Shilagardi, et al., <i>Science</i>, 7 March 2013 (10.1126/science.1234781). Reprinted with permission from AAAS.

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