Rice University Researchers (IMAGE) Rice University Caption Rice University researchers, from left, José Onuchic, Herbert Levine and Federico Bocci brought together computational models at the Center for Theoretical Biological Physics that established the central role of a ligand, JAG1, that helps cancer cells differentiate to confound therapies as well as metastasize. Credit Jeff Fitlow/Rice University Usage Restrictions Credit must be used. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.