Anchored Protein Synthesis (IMAGE)

Wiley

Anchored Protein Synthesis

Caption

The chemical synthesis of a cysteine-modified glycosylphosphatidylinositol anchor provides access to homogeneous GPI-anchored prion protein through expressed protein ligation. By this method, it should be possible to investigate the influence of the complex post-translational GPI modification on protein structure and function.

Credit

(C) Wiley-VCH 2008

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Permission to use with appropriate credit and link to http://dx.doi.org/10.1002/anie.200802161

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