MRI Detects Early Breast Cancer Metastases in Mice (IMAGE)

NIH/National Institute of Biomedical Imaging & Bioengineering

MRI Detects Early Breast Cancer Metastases in Mice

Caption

Metastasis occurs when cells are shed from primary breast cancer tumor and establish a new tumor at a distant site. For early detection of the metastasis with MRI, the Lu Lab at Case Western University developed a probe that binds to fibrin-fibronectin protein complexes in high-risk tumors. Fibronectin is expressed in high-risk (aggressive) cancer and not in normal tissue, so MRI imaging is able to distinguish metastases from normal tissue.

Credit

Lu Lab, CWRU.

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