Evolutionary History of a Hypothetical Multidomain Family (IMAGE)
Caption
Multidomain families evolve on three levels of organization: species, the gene family, and co-evolving domains. This example shows the evolutionary history of a hypothetical multidomain family with four present-day genes, k1?k4, in two species. These genes encode multidomain proteins; domains are shown in pink, blue, and green. The composite evolutionary history of the gene family is depicted as domain trees embedded within a gene tree (cream), which is, in turn, embedded in a species tree (gray). The goal of the EAGER grant, Design Rules for Multidomain Proteins Across the Tree of Life, is to infer the principles which shape this evolutionary process.
Credit
Maureen Stolzer and Dannie Durand, Carnegie Mellon University
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Credit: Maureen Stolzer and Dannie Durand, Carnegie Mellon University
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