The Principle of the Measurement of Blood Coagulability and the Index for Factor Xa Activity (IMAGE)

_Tokyo Medical and Dental University

The Principle of the Measurement of Blood Coagulability and the Index for Factor Xa Activity

Caption

(top) Citrated whole blood is put between electrodes. When the blood starts coagulation, the permittivity measured by alternating current (AC) increases in relation to the aggregation and deformation of blood cells.

(bottom) Temporal change in normalized permittivity at 10MHz is extracted, and the derivative is calculated. The time to reach the maximum value of the derivative is defined as maximum acceleration time (MAT).

Credit

Department of Biofunctional Informatics,TMDU

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